Cardiology

Quick Take: Ultra-processed food intake and risk of cardiovascular disease

The consumption of ultra-processed food has increased substantially over the last several decades. These foods often have higher proportions of total and saturated fat, added sugar, energy density and salt, and lower proportions of fiber and vitamin density. Limited cross-sectional data has suggested associations with obesity, metabolic syndrome, functional gastrointestinal Czytaj więcej…

Artificial intelligence

AI helps to predict risk of a potentially fatal heart disease

reprint An artificial intelligence algorithm is able to identify a patient’s risk from a cholesterol-raising genetic condition that has a 20-fold increased risk of coronary artery disease if untreated. Individuals with the potentially fatal heart disease—called familial hypercholesterolemia (FH)—carry a mutation that interferes with their bodies’ ability to clear low-density Czytaj więcej…

Cardiology

Quick Take: Effect of a Multifaceted Quality Improvement Intervention on the Prescription of Evidence-Based Treatment in Patients at High Cardiovascular Risk in Brazil

In low and middle-income countries, the implementation of evidence-based therapies for cardiovascular disease, including the use of statins, antiplatelet therapy and anti-hypertensive medications, remains a challenge, despite high associated morbidity and mortality. In this cluster randomized controlled trial, 1619 patients with established atherosclerotic disease from 40 public and private outpatient Czytaj więcej…

aortic stenosis

#VisualAbstract: Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

1. This randomized control trial compared post-surgical outcomes between transcatheter aortic-valve replacement (TAVR) with balloon-expandable valves or surgical valve replacement in low- risk surgical patients, finding that patients randomized to receive TAVR had significantly lower rates of composite death, stroke or rehospitalization after one year. 2. Patients randomized to the Czytaj więcej…

ambulatory blood pressure

Catheter-based renal denervation reduces blood pressure in patients with uncontrolled hypertension

1. Meta-analysis of sham-controlled randomized trials of catheter-based renal denervation demonstrated reduction in ambulatory and office systolic blood pressures. 2. Second-generation trials demonstrated greater reduction in ambulatory systolic blood pressure compared to first generation trials. Evidence Rating Level: 1 (Excellent) Study Rundown: Hypertension is one of the most common adult Czytaj więcej…