blood donor

Blood transfusions from female, previously pregnant, or sex-discordant donors do not increase mortality

1. In this large retrospective cohort, there were no increases in mortality from red blood cell transfusions from female, previously pregnant, or sex-discordant donors. Evidence Rating Level: 2 (Good) Study Rundown: Recently, a few studies have suggested that blood donation from female donors, especially to male recipients, may result increased Czytaj więcej…

Cardiology

Unrecognized myocardial infarctions associated with embolic cerebral infarctions of undetermined source

1. In this cross-sectional cohort study of older adults in Iceland, MRI findings of myocardial infarction was associated with coincident MRI findings of cerebral infarction. 2. Patients with embolic patterns of cerebral infarction, without a clear source, had a higher likelihood of unrecognized myocardial infarction diagnosed by MRI. Evidence Rating Czytaj więcej…

Cancer

Quick Take: Treatment and Long-Term Clinical Outcomes of Incidental Pulmonary Embolism in Patients With Cancer

Venous thromboembolism (VTE) is a common complication in patients with cancer. Often, VTEs are incidentally detected on imaging studies undertaken for cancer staging or evaluation of treatment response. Current guidelines recommend that the same anticoagulant treatment be used for both incidental pulmonary embolism (PE) and symptomatic PE in patients with Czytaj więcej…

chronic disease

Sodium-glucose cotransporter-2 inhibitors may be linked to Fournier gangrene

1. In this descriptive case series, 55 cases of patients with diabetes who developed Fournier gangrene while using sodium-glucose cotransporter-2 (SGLT2) inhibitors are described. 2. While neither causality nor incidence are identified in this paper, physicians prescribing SGLT2 inhibitors should be aware of the association with Fournier gangrene. Evidence Rating Czytaj więcej…