atrial fibrillation

Direct oral anticoagulants for atrial fibrillation in patients with mitral stenosis

1. In this retrospective observational study, direct oral anticoagulant use for atrial fibrillation in patients with mitral stenosis was linked with decreased mortality and fewer thromboembolic events compared to warfarin.  2. There was also a non-significant trend towards fewer episodes of intracranial hemorrhage with direct oral anticoagulant use. Evidence Rating Czytaj więcej…

bag-mask ventilation

The PreVent trial: bag-mask ventilation decreases hypoxia in patients undergoing tracheal intubation

1. For intensive care unit (ICU) patients undergoing tracheal intubation, bag-mask ventilation between induction and laryngoscopy resulted in less hypoxia during the procedure. 2. No difference in aspiration was reported for patients in the groups undergoing intubation with or without bag-mask ventilation. Evidence Rating Level: 1 (Excellent)       Study Rundown: A Czytaj więcej…

capillary refill time

Peripheral perfusion-targeted resuscitation does not lower mortality in septic shock patients

1. In this randomized controlled trial, there was no difference in 28-day mortality in patients with early septic shock between peripheral perfusion-targeted resuscitation and lactate level-target resuscitation strategies. 2. There was significantly less organ dysfunction at 72 hours in the peripheral perfusion group. Evidence Rating Level: 2 (Good) Study Rundown: Czytaj więcej…

acute decompensated heart failure

The PIONEER-HF Trial: Sacubitril-valsartan linked to superior outcomes in acute decompensated heart failure

1. Among patients hospitalized for acute decompensated heart failure with reduced ejection fraction (HFrEF), treatment with sacubitril-valsartan reduced N-terminal pro-B type natriuretic peptide (NT-proBNP) greater than treatment with enalapril. 2. There was no significant difference in the rate of worsening renal function, hyperkalemia, symptomatic hypotension, or angioedema between either treatment Czytaj więcej…

Emergency

Quick Take: Impact of scribes on emergency medicine doctors’ productivity and patient throughput: multicentre randomised trial

Medical scribes are used in variety of clinical settings to complete clerical tasks otherwise done by a clinician. Limited research has been done concerning the effects of scribes on physician productivity in emergency medicine settings. In this randomized controlled trial from Australia, data were collected from 589 scribed shifts (5,098 Czytaj więcej…

Concussion

Individualized exercise program linked to faster recovery following pediatric sport-related concussion

1. In this randomized control trial of pediatric sport-related concussion (SRC), a progressive sub-symptom threshold aerobic exercise program was linked to a shorter time to recovery compared to a placebo stretching program. 2. The sub-symptom threshold exercise program also demonstrated a non-significant trend towards reduced risk of delayed recovery. Evidence Czytaj więcej…

Aspirin

Aspirin use associated with reduction in cardiovascular events but increase in bleeding risk

1. In this systematic review and meta-analysis, while aspirin use among patients without cardiovascular disease was associated with fewer adverse cardiovascular events, it was not associated with a reduction in all-cause mortality. 2. The use of aspirin in patients without cardiovascular disease was associated with increased risk of major bleeding. Evidence Czytaj więcej…