heart failure

#VisualAbstract: Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure

1. In this randomized controlled trial, the injection of mesenchymal precursor cells into the myocardium of patients undergoing a Left Ventricular Assist Device (LVAD) implant did not increase successful temporary weaning from device support. 2. Left ventricular ejection fractions (LVEFs) and quality of life scores were similar between groups. Evidence Czytaj więcej…

Cardiology

Mesenchymal precursor cell transplant did not improve weaning from device support in LVAD patients

1. In this randomized controlled trial, the injection of mesenchymal precursor cells into the myocardium of patients undergoing a Left Ventricular Assist Device (LVAD) implant did not increase successful temporary weaning from device support. 2. LV Ejection Fractions (LVEFs) and quality of life scores were similar between groups. Evidence Rating Czytaj więcej…

heart failure

#VisualAbstract: Effect of Patient-Centered Transitional Care Services on Clinical Outcomes in Patients Hospitalized for Heart Failure

1. In this randomized controlled trial, patient-centered transitional care services did not improve a composite of clinical outcomes in hospitalized heart failure patients. 2. Patients who received transitional care had improved discharge readiness scores. Evidence Rating Level: 1 (Excellent) Study Rundown: Heart failure (HF) is a leading cause of hospitalizations in Czytaj więcej…

Cardiology

Patient-centered transitional care services unlikely to benefit hospitalized heart failure patients

1. In this randomized controlled trial, patient-centered transitional care services did not improve a composite of clinical outcomes in hospitalized heart failure patients. 2. Patients who received transitional care had improved discharge readiness scores. Evidence Rating Level: 1 (Excellent) Study Rundown: Heart failure (HF) is a leading cause of hospitalizations Czytaj więcej…

90-day postoperative mortality

Symptomatic and non-symptomatic heart failure associated with increased postoperative mortality in non-cardiac elective surgery

1. In this retrospective cohort study, 90-day postoperative mortality after non-cardiac surgeries was higher for patients with symptomatic or non-symptomatic heart failure than patients without. 2. Postoperative mortality increased with decreasing ejection fraction. Evidence Rating Level: 2 (Good) Study Rundown: Heart failure is an important risk factor for postoperative mortality. Czytaj więcej…

Cardiology

Hospital Readmissions Reduction Program associated with increased 30-day post-discharge mortality for heart failure and pneumonia                                                      

1. In this retrospective cohort study, implementation of the Hospital Readmissions Reduction Program (HRRP) was unexpectedly associated with an increase in 30-day post-discharge mortality for heart failure and pneumonia but not for acute myocardial infarction. 2. There was a lack of association between the HRRP implementation and 45-day post-discharge mortality. Czytaj więcej…

chronic disease

MitraClip does not significantly improve outcomes in secondary mitral regurgitation: the MITRA-FR trial

MitraClip 1. Among patients with heart failure with reduced ejection fraction (HFrEF) and severe secondary mitral regurgitation on medical therapy, percutaneous mitral valve repair did not significantly reduce 12-month rates of death or hospitalization due to heart failure when compared to medical therapy alone. 2. Percutaneous mitral valve repair was Czytaj więcej…

Cardiology

The COAPT: Transcatheter mitral valve repair lowers mortality in patients with heart failure and mitral regurgitation

1. Patients with heart failure and severe secondary mitral valve regurgitation randomized to receive transcatheter mitral valve repair had decreased rates of all-cause mortality and hospitalizations after 24 months compared to patients treated with medical therapy alone. 2. For patients undergoing valve repair, the rate of freedom from device-related complications Czytaj więcej…

Cardiology

Baseline physical activity in patients with heart failure influences cardiovascular outcomes: the HF-ACTION Trial

1. In this study of patients with chronic systolic heart failure, baseline physical activity (PA) was linked with greater exercise performance, lower symptom class, lower depression, and lower incidence of atrial fibrillation. 2. Responses to physical activity training were not different between baseline physical activity tertiles, suggesting benefit of exercise Czytaj więcej…